الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Cancer is one of the most dangerous diseases in the world. Many trials were attempted to synthesize anti cancer drugs adopting quinoxaline ring as a main core. So, by means of molecular modeling studies (docking techniques), we managed to build new penylaminoquinoxaline derivatives as anti cancer and they were biologically screened for their activity.The adopted reactions afforded twenty one new compounds that were not mentioned in the available literature. Structure elucidation of the newly synthesized compounds was achieved through IR, 1H-NMR, 13C-NMR, elemental analysis and Mass spectroscopy.Molecular modeling evaluation was carried out using molegro virtual docker (MVD) software to predict the expected activity of the newly synthesized compounds.The newly synthesized compounds have been subjected for preliminary in vitro growth inhibitory (GI) activities against liver carcinoma cell line HEPG2 cell line using Sulphorhodamine-B method (SRB). The biological evaluation showed that mostly of the synthesized compounds showed more than 50% GI and some of them showed promising activity with GI more than 70%.