الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 32 |  |  |
| | | from | 32 | | |
Abstract
Chronic liver disease can change many aspects of life of the patients and their family and effects society as complications that contribute to repeated hospitalization in such patients and markedly impair their quality of life. This study was conducted to assess the impact of chronic liver disease on a weighted score of health – related quality of life in those patients. This study was conducted on one hundred and fifty patients and fifty persons controls selected from out and /or inpatient clinics of tropical medicine in Menoufiya University Hospital and Shebine EL-Kom fever hospital in the period from April 2014 to December 2014 . Patients were subdivided into the following groups: - Group I :50 patients with chronic liver disease Child A - Group II :50 patients with chronic liver disease Child B - Group III:50 patients with chronic liver disease Child C. - Group IV: 50 persons normal individual controls chosen from their relatives or neighbours.. All patients were subjected to the following Complete history taking. Full clinical examination Laboratory investigations :( CBC, ESR, Urine, stool analysis, Urea, creatinine, Fasting and postprandial blood glucose, Liver functions and Serological tests)
Abdominal ultrasonography. Calculation Child – turcotte –Pugh(CTP) score. Patients are subjected to the Medical Outcomes Study short form 36 (SF-36) questionnaire; generic health-related quality-of-life questionnaire. SF-36 consists of 36 items divided into 8 scales that can be aggregated into 2 summary scores: a mental Component summary and a physical component summary. The eight scales are (1) physical functional ability, (2) role (behavior) due to physical impairment, (3) bodily pain, (4) general health, (5) vitality, (6) social functioning, (7) role (behavior) due to emotional impairment and (8) mental health. Scores for these 8 SF-36 scales range between 0 and 100 . All patients completed a Medical Outcomes Study short form 36 (SF-36) questionnaires which is a widely generic questionnaire used for measuring quality of life in different chronic diseases. Increasing disease severity (Child scoring) and related complications were associated with a poor quality of life, particularly for the physical and mental component as it decreases with child C more than child B and A. With increasing of education scores of physical fitness and vitality of patients increases. Occupation allows the patients to practice regular physical activity in order to maintain and improve their physical fitness and vitality. On the other hand there no difference in quality of life scores concerning to residence of patients, gender, marital state, age. Prevention, early diagnosis and treatment of the underlying causes of chronic liver diseases are must to avoid development of the disease and its effect on quality of life proper choice and monitoring of the treatment used in hepatic patients with liver cirrhosis due to effect on their quality of life. Physical and mental reassurance of the chronic hepatic patients due to liver cirrhosis as their quality of life is worse with progression of disease.