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Abstract Resveratrol and the root of Rumex sp. have a wide variety of applications in life. The objective of the present study was to investigate the effect of resveratrol and the root of Rumex sp. as antioxidants and to evaluate their radioprotective roles against radiation induced chromosomal aberrations in mice bone - marrow cells. To carry out this study, 80 male mice were divided into 16 groups, 5 animals in each group. Animals received single i.p dose of resveratrol (50, 100mg/kg.bw) and repeated dose of 50mg/kg.bw 30 minutes befor irradiation with a dose of 4 GY γ- ray. Other groups of animals received single i.p dose of rumex (25,50mg/kg.bw) and repeated dose of 25mg/kg.bw 30 minutes befor irradiation. Animals were sacrificed 24 hrs after irradiation and 50 metaphases spreads were examined per animal for chromosomal aberrations. |