الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Timing of sentinel lymph node biopsy in the context of neoadjuvant chemotherapy continues to evolve; there is some evidence that primary chemotherapy may modify lymphatic drainage which can affect the identification rate of the sentinel node.The concerns regarding sentinel node biopsy after neoadjuvant chemotherapy are: the possible lymphatic alterations after neoadjuvant chemotherapy and the unequal effect of the sentinel and the non-sentinel nodesIt is suggestive that until more data are available on the safety and appropriate use of SNB after NAC, we must maintain an evidence-based and a cautious approach to the management of patients with suspected or known nodal metastasesIn our study, we evaluated the feasibility and accuracy of SLNB using methylene blue dye in axillary staging in breast cancer patients after neoadjuvant chemotherapy from our study we conclude that:•Methylene blue dye is a cheap, efficient alternative for patent blue dye with less allergic reactions in performing sentinel LN biopsy. However combined approach (dye & isotope) remains superior to a single method approach as regard both detection & false negative rates•SLNB is patients with T4 breast cancer after neoadjuvant chemotherapy is associated with low detection rate & high false negative rate making it doubtful technique for axillary staging• SLNB should be adopted to be the standard method for axillary staging in breast cancer patients with T1-3 tumors after receiving neoadjuvant chemotherapy.