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العنوان
Effects of some anabolic drugs on testicular function of albino rats /
المؤلف
Younes, Osama Moftah.
هيئة الاعداد
باحث / أسامة مفتاح يونس
مشرف / حسن إبراهيم الصياد
مشرف / دعاء عبدالحميد صقر
مناقش / أمينة عيسوي عيسوي
الموضوع
Cytology. Histology. Embryology.
تاريخ النشر
2015.
عدد الصفحات
154 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of Zoology
الفهرس
Only 14 pages are availabe for public view

from 180

from 180

Abstract

Introduction:- Athletes and bodybuilders consumed high protein supplements to obtain energy and enhance the development and strength of their muscles. Over time different investigations have revealed dysfunctions of their body organs. There are contradictions between scientists concerning the benefits and the alarm of developing body dysfunction. Methods: We assigned male Wistar albino rats to 3 groups(n=10 each), control, hyperwhey protein (2.5g/kg body weight) and super amino 2500. (2.5g/kg body weight). The applied dose was orally administered daily in tap water for 14 weeks. Results: Hyperwhey and super amino 2500 supplemented rats had lower body weight gain in comparison with the control and developed organs dysfunction manifested by apparent congestion of blood vessel, reduction of spermatogenic cells and edematous lesions in between Seminiferous tubules of testis, vacuolar degeneration of follicle cells and reduction of thyroglobulin of thyroid, increased apoptosis and breakdown of hepatocyte and spermatogenic cell. SA had thickening of the liver capsule and more drastic damage of hepatocytes. The level of transaminases was markedly increased. Also insulin level was markedly decreased in parallel with increase cholesterol, LDL and triglycerides as well as decrease T3,T4 and testosterone. Conclusion: Hyperwhey and super amino protein formula administration dramatically altered the liver function and increased hepatic damage similar to the development of suspected diabetes ,damage of thyroid follicles confirmed by depletion of T3 & T 4 and Impaired testis function and increased sperm abnormalities and decrease testosterone.