الفهرس 
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Abstract
The present work was devoted to investigate the development of stabilized and densely dispersed chitosan-zinc hybrid nanoparticles (CS-Zn NPs) using a new eco-friendly “green” approach based on electrochemical oxidation /complexation process followed by UV irradiation, ascorbic acid and NaBH4 reduction. The synthesized CS-Zn NPs were characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), atomic absorption, Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), zeta potential and UV–Vis spectroscopy. These characterizations were carried out to specify the functional groups, crystalline structure, average grain size and size distribution of the developed CS-Zn NPs. The obtained CS-Zn NPs were pellets in shape by using NaBH4, spherical when using ascorbic acid and truncated octahedral by UV irradiation. Average particle size found to be about 40, 22, and110nm by using ascorbic acid, NaBH4 and UV irradiation as reducing agents.
The CS-Zn NPs synthesized in the present study also demonstrated a relatively strong antibacterial activity as compared to that of control (CS) by using the nutrient agar disc diffusion method with determination of the inhibition zones (mm). The obtained results revealed that the CS-Zn NPs developed in this study could be useful in various biological and biomedical applications.