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العنوان
Evaluation of some analgesics for pain management in urologic surgery in ruminants /
المؤلف
Hamed, Mohammed Ali Mohammed.
هيئة الاعداد
باحث / محمد على محمد حامد
مشرف / جمال إبراهيم عبدالفتاح قروف
مشرف / عصام مصباح محمد محمود
مشرف / مصطفى أحمد محمود أبونورج
مشرف / عوض زعبله حسن رزق
الموضوع
Anesthesia. Ruminants. Pain - drug therapy.
تاريخ النشر
2015.
عدد الصفحات
84 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة المنصورة - كلية الطب البيطرى - Department of Surgery, Anesthesiology and Radiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study was performed in Surgery, Radiology and Anesthesiology Dept. Faculty of Veterinary. Medicine, Mansoura University Sixteen apparently healthy bucks (aged 8-18 months; average body weight (15-25) kg were used. All animals free from concurrent diseases. All animals were housed in surgery clinic and kept in individual free stalls on straw bedding and were fed a diet based on hay and concentrates. No analgesics were given within one week before the experiment. Food was withheld for 24 hours and water was for 12 hours before para median tube cystostomy. Animals used in this study were randomly assigned into (4) groups, four animals for each group. All bucks were infiltrated with lidocaine hydrochloride 1 % in a dose of 8 ml, 15 mins before applying surgery. Initial administration of meloxicam at dose of 0.5 mg/kg took place before surgery on d 0 and was then repeated once daily for another 4 consecutive days postoperatively in groups MBL, MML and MDL. Group I: Lidocaine (L): Bucks were restrained into lateral recumbency for application of linear infiltration analgesia at surgical site by lidocaine hydrochloride 1%. Group II: (MBL): Animals in this group were intravenously (I/V) received meloxicam then after 15 mins, butorphenol at dose of 0.2 mg/kg then restrained into lateral recumbency for infiltration of lidocaine hydrochloride 1%. Group III: (MML): Animals in this group were I/V received meloxicam then after 15 mins midazolam at dose of 0.5 mg/kg then restrained into lateral recumbency for infiltration of lidocaine hydrochloride 1%. Group IV:(MDL): Bucks in this group were I/V received meloxicam then after 15 mins dexmedetomidine at dose of 5µg/kg then restrained into lateral recumbency for infiltration of lidocaine hydrochloride 1%. Preemptive treatment with dexmedetomidine (5 ug/kg BW) combined with meloxicam (0.5 mg/ kg BW) appears to be the best combination for alleviation of surgical stress and pain perception in bucks undergoing tube cystostomy. Meloxicam appears to be safe for the gastrointestinal tract and used for long term treatment of pain without complication.