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العنوان
Impact of osteon 2 collagen in bone formation in diabetic rats /
المؤلف
Msaik, Mohnned Aboa-Lgasem Mohamed.
هيئة الاعداد
باحث / مهند أبوالقاسم محمد أمسيك
مشرف / أحمد صبحي سليم
مشرف / هبة محمود السبعة
مشرف / عبدالمنعم توفيق جادالله
الموضوع
Diabetic rats. Disease Models, Animal.
تاريخ النشر
2015.
عدد الصفحات
106 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Oral Surgery
تاريخ الإجازة
01/01/2015
مكان الإجازة
جامعة المنصورة - كلية طب الأسنان - Oral & Maxillofacial Surgery Department
الفهرس
Only 14 pages are availabe for public view

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Abstract

Background: Diabetes mellitus is accompanying with an extensive list of problems, it is often associated with reduced bone mass and delayed fracture healing. The bone graft is one of the first choices selected in this problem. Purpose: The aim of this study was to evaluate the use of osteon 2 collagen in bone development in diabetic rats.
Materials and Methods: group A left side (A-LS) ► osteon 2 collagen free sub groups and group A right side (A-RS) ► osteon 2 collagen subgroup. group B left side (B-LS) ► osteon 2 collagen free sub groups. And group B right side (B-RS) ► osteon 2 collagen subgroup. Each group was further histological assessment either at 1th, 2nd, 4th and 6th weeks of follow up. Results: Histological examination showed that the bone healing was increased and enhanced with new bone graft material (osteon 2 collagen) in diabetic animal. Conclusion: Created on the previous results we conclude that administration of osteon 2 collagen in diabetic rats with mandibular bone defect leads to Enhancement of matrix formation resulting in acceleration in the rate of diabetic bone healing and increased activity of bone formation resulting in acceleration of the rate of diabetic bone healing.