الفهرس 
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Abstract
Periodontitis is an inflammatory infectious disease of the peridontium. Aggrissive periodontitis is a relatively rare, sever and rapidly progressive form of periodontitis, characterized by rapid loss of alveolar bone, early age of onset (circumpubertal) and tendency for familial aggregation, more common in females than males, it has the localized and generalized form. The amount of destruction manifested is not proportionated with the amount of local irritants present. Conventional treatment depends always on the concept of plaque control and bacterial eradication by means of nonsurgical and/or surgical therapy. Scaling and root planning as the basic periodontal treatment has its limitations, so new treatment modalities are needed, to be used as an adjunct to conventional treatment or as a treatment of its own. The use of low power laser was suggested as an adjunctive treatment modality to basic nonsurgical periodontal treatment, as it was proven earlier to have a positive biomodulatory effect on biological tissues if suitable parameters were used for the condition in hand. Low power diode laser 810 nm was used in this study The patients participated in the current study were all diagnosed with mild to moderate aggressive periodontitis with bilateral defects, and were all medically free to exclude any factors that could affect the periodontal condition of the patients, periodontal wound healing, and consequently the final results of the study. The selected patients were assigned in a split mouths design clinical trial for the purpose of standardization of response of treatment and better comparing of the final results. The defects found on the right side of the patients were assigned to the laser group which received both conventional treatment in addition to laser treatment, on the other hand, the defects found on the left side of the patients were assigned to the control group in which only conventional treatment was receive. The clinical parameters used for evaluation included periodontal pocket depth, clinical attachment loss, plaque index, modified gingival index, and gingival recession. These measurements were taken at baseline and at 3 months. Bone density was recorded by means of analyzing radiographic films taken at baseline and at 6 months. Transformer growth factor beta 1 was screened by collecting gingival crevicular fluid samples at baseline and at 1, 2, 3, and 4 weeks after treatment. The results of this study showed a significant decrease of PPD and CAL in favor of laser group, on the other hand PI, MGI, and GR showed no significant difference between both groups, bone density showed a significant increase in favor of laser group, and finally TGF-β1 showed a significant steady decrease between baseline and all following time points in the laser group.