الفهرس 
Hepatitis C Virus (HCV) InfectionOnly 14 pages are availabe for public view
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Abstract
Egypt has one of the highest rates of reported infections with hepatitis C virus (HCV), largely attributed to the use of contaminated parenteral antischistosomal therapy. chronic hepatitis C (CHC) infection is associated with wide spectrum of liver histological lesions ranging from mild chronic hepatitis to cirrhosis and hepatocellular carcinoma (HCC).The HCV is both hepatotropic and lymphotropic. Replication of HCV in diseased extrahepatic organs and tissues may either trigger latent autoimmunity or induce autoimmune disorders. In addition to established liver injury, type-2 diabetes Mellitus(DM) is an important feature of extrahepatic metabolic disorders which are attributed to HCV infection. When DM is resent, it seems not only to accelerate the course of CHC infection but also to influence the response to antiviral therapy.