الفهرس 
Abstract
Histopathology of dental cariesOnly 14 pages are availabe for public view
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Abstract
This study was designed to evaluate micromorphological changes and microtensile bond strength of three different adhesive systems bonded to caries-affected dentin (CAD) pretreated with remineralizing agent casinephosphpeptide-amourphous calcium phosphate (CPP-ACP). A total of 90 extracted human maxillary third molar teeth with moderate carious lesions and 30 sound third molar teeth scheduled for periodontal reasons, were selected for this study. The 120 teeth were divided into four groups. 30 molars each, according to remineralizing agents application. Group A non-carious teeth as a negative control, Group B teeth with moderate caries as positive control, Group C pretreated with non-fluoridated CPP-ACP, Group D pretreated with fluoridated CPP-ACPF. Each group was subdivided into three subgroups, according to the adhesive system (n=10). After sectioning of the samples into longitudinal sticks of 1mm diameter, microtensile bond strength (µTBs) was measured at strain rate of 0.5mm/min. Data was analyzed using Two-way ANOVA, (SPSSTM soft were), independent samples (Shapiro-wilk test, post-hoc Tukey test). Bond strength of E&R adhesive systems to ND was significantly higher than that to CAD,CAD/CPP-ACP,CAD/CPP-ACPF.On the other hand, there were no significant difference between ND groups bonded with one- step SE and two-step SE adhesive systems, and that to CAD, CAD/CPP-ACP, and CAD/CPP-ACPF. Untreated CAD showed the lowest µTBS (P< 0.05) than the other groups regardless the bonding system used. There were no significant difference between µTBs of CAD, CAD/CPP-ACP, and CAD/CPP-ACPF. (P< 0.05) Within the limitation of the study and based on the finding. We can concluded that 1. The Pretreatment of CAD surface with CPP-ACP can be used clinically to improve bond strength of a etch-and rinse adhesive resins, and a self-etch one-step adhesive to remaining dentin. 2. Self-etch (SE) adhesives were developed to simplify the bonding process by reducing the number of application steps, but this development gave rise to trade-offs in the quality of resin bonds. 3. Etch-and-rinse (E&R) adhesive still a promising approach for bonding to normal dentin, however doesn’t enhance bonding to CAD either with or without pretreatment with CPP-ACP agents.