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Abstract - The present study was carried out to compare pupil cantered versus corneal vertex centered ablation in LASER - assisted in-situ keratomileusis (Lasik) correction of hyperopia. - The study was conducted over 40 eyes of 20 patients with hyperopia; the ablation was centered on the pupil in 20 eyes, while it was centered on the corneal vertex in the other 20 eyes. Exclusion criteria were: any abnormal ocular condition such as: Nuclear sclerosis of the lens. History of eye disease, such as glaucoma or herpetic keratitis. Any optical opacities or pathology on slit-lamp such as corneal opacities, cataract …etc. Previous ocular trauma or intraocular surgery. Corneal diseases such as corneal dystrophies. Ocular infections. All cases had undergone through examinations including: - Manifest refraction. - Cycloplegic refraction. - Slit-lamp microscopic evaluation of the anterior segment. - Fundus examination after pupil dilatation. - Intraocular pressure measurement using applanation tonometry (Goldmann). - Best corrected visual acuity (BCVA) and uncorrected visual acuity (UCVA). - Corneal topography and ultrasound pachymetry. - The relative positions of pupil centers and corneal vertex were registered by means of topographic coordinates (dxtopo and dytopo). - Before LASIK procedure, corneal images were obtained using high resolution pentacam. Main outcome measures: Primary outcome measure was the safety index. Main secondary outcome measures were efficacy index, manifest refraction, uncorrected visual acuity, best spectacle-corrected visual acuity (BCVA). Results showed that the safety index in the pupil centered group was 0.98 ± 0.06, while it was 0.97 ± 0.07 in the vertex centered group. Also, Results showed that the efficacy index in the pupil centered group was 0.95 ± 0.09, while it was 0.94 ± 0.09 in the vertex centered group. At the end of this study, it was concluded that LASIK is an effective and safe procedure for treatment of hyperopia whether pupil-centered or vertex-centered. |