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Abstract Bacteremia is usually defined as the presence of viable bacteria in the blood stream, as evidenced by blood cultures. Bacteremia was responsible for the high increase in the mortality rate in old patients with coexisting chronic diseases. As bacteremia was ranked the 10th leading cause of death constituting the largest group of severe infections with known microbial etiology specially pneumonia and UTI. Diabetes mellitus (DM) describes a metabolic disorder of multiple etiology characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The effects of diabetes mellitus include long–term damage, dysfunction and failure of various organs. Diabetes mellitus is the fifth most common cause of death in the world and it is estimated that one in eight deaths (12.2%) among 20 to 79-year-olds were attributable to this condition in 2010. Several factors could predispose diabetic patients to infections including bacteremia. These factors include genetic susceptibility to infection; altered cellular and humeral immune defense mechanisms; local factors include poor blood supply and nerve damage and alterations in metabolism associated with diabetes. chronically ill and immunocompromized patients with D.M have an increased risk of bacteremia. They may also develop bacteremia and fungimia. |