الفهرس 
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Abstract
The present study aimed to test the efficacy of adding 100 μg dexmedetomidine to bupivacaine on duration and quality of intraoperative anesthesia and postoperative analgesia for patients undergoing below knee surgery using ultrasound-guided femoral–sciatic nerve block.
After ethical approval, 60 patients aged 18-60 years old, with an American Society of Anesthesiologists (ASA) physical class from I to II who underwent below knee surgery using combined femoral-sciatic anesthesia, were included in this prospective, randomized, double-blinded study.
Patients were randomly assigned to receive bupivacaine alone divided (group B) or dexmedetomidine 100 μg added to bupivacaine (group BD) [n = 30 for each group] for combined femoral–sciatic nerve block
Onset and duration of sensory and motor blocks were assessed along with the duration of analgesia, and adverse effects, if any. Hemodynamic parameters, like heart rate (HR), systolic arterial blood pressure (SBP), and diastolic arterial blood pressure (DBP) were also monitored.
This study showed that the addition of dexmedetomidine 100 μg to bupivacaine during ultrasound-guided combined femoral-sciatic nerve block for below knee surgery was associated with +75% longer duration of analgesia, -20% shorter onset times for sensory and motor block, -25% faster time for surgical readiness, and longer duration of sensory and motor block (+45% and +40%, respectively).