الفهرس 
Epidemiology of Colorectal Cancer
Prior colorectal cancer or polyps:Only 14 pages are availabe for public view
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Abstract
Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. (1) In Egypt, CRC ranked sixth in both males and females representing 4.1 % of all incident cancers based on Gharbia population-based regional cancer registry. (2 Almost 50% of patients with CRC will develop metastases despite aggressive initial management of the primary tumor, and 25% of colorectal cases present with metastases at initial diagnosis. (3, 4 Liver is the most common site of involvement with 20% to 34% of patients with colorectal cancer present with synchronous liver metastases. (5, 6)
The goals of chemotherapy for metastatic colorectal carcinoma (mCRC)differ according to the clinical scenario. For most patients, treatment will be palliative and not curative - a fact that patients may not understand -and the treatment goals are to prolong overall survival and maintain quality of life (QOL) for as long as possible