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العنوان
Value of 18-FDG PET/CT in assessment of solitary
pulmonary nodule
/
المؤلف
Keshk,Mohammed Ashraf Mohammed
هيئة الاعداد
باحث / مد أشرف محمد كشك
مشرف / ميرفت محمد إبراهيم الجوهري
مشرف / ماري يفتاح تادرس بطرس
تاريخ النشر
2015.
عدد الصفحات
201.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/10/2015
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

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from 32

Abstract

FDG-PET/CT provides powerful information on tumor characteristics – both morphologic and functional. In addition to providing accurate functional/anatomic correlation, the CT scan clearly detects smaller pulmonary metastases that are below the resolution of PET.
18 FDG PET/CT helps characterize SPN, as most of malignant nodules show increased glucose metabolism. The diagnostic accuracy of 18 FDG PET depends on the size of the nodule and its avidity for 18 FDG, and false-negative studies have been reported in nodules smaller than 1 cm, well-differentiated adenocarcinoma, bronchio-alveolar cell carcinoma, and carcinoid.
False-positive findings include infectious and inflammatory processes such as tuberculosis, fungal infections, and sarcoidosis. It has been reported that 18 FDG PET/CT can reliably characterize SPN more than 7 mm providing valuable information to guide patient management, especially useful where biopsy is risky, in elderly patients, or when there is a low risk for malignancy. This, SNPs with increased 18 FDG uptake are likely malignant and should undergo further invasive resection or biopsy. However, nodules PET negative still need to be followed (usually by CT) because of the possibility of false-negative PET finding.
PET/CT offers a number of advantages in radiation therapy, including reduced risk of geographic misses; a minimized dose of ionizing radiation to non-target organs, definition of radiation treatment field of tumor in atelectasis. Also it plays a major role in follow up of malignant tumors and their response to therapy.