الفهرس 
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Abstract
This work was carried out to study the prevalence of Beta-Lactam antibiotic and their public health hazards in raw milk and some dairy products. A total of 95 milk samples included 44 bulk raw milk samples (17 samples each of cow’s bulk raw milk and buffalo’s bulk raw milk and 10 ewe’s individual raw milk samples), 30 marketed raw milk samples and 21 pasteurized milk samples were collected randomly from different private milking farms and markets in Dakahlia province, Egypt. The samples were qualitatively analyzed by Delvotest SP NT. The results revealed that antibiotic residues were detected in 8(18.2%) out of 44 farm raw milk samples of which 4(23%) out of 17, 2(18.2%) out of 17 and 2(20%) out of 10 samples of cow’s bulk raw milk, buffalo’s bulk raw milk and ewe’s bulk raw milk, respectively. While 4(13.3%) out of 30 marketed raw milk samples contained antibiotic residues. All pasteurized milk samples were negative. High performance liquid chromatography (HPLC) used for detection of Betalactam residues in positive samples which revealed that Betalactam residues were identified in 3 samples (6.8%) of farm raw milk samples in which penicillin level was 1370.34µg/L and 3621.71µg/L in two cow’s bulk raw milk samples and 6682.83µg/L in one of the buffalo’s bulk raw milk sample. Betalactam residues were identified in 13.3% of marketed raw milk, whereas Penicillin levels ranged from 15.96 to 16.8µg/L with a mean of 16.39 ± 0.1546µg/L, while Amoxicillin levels ranged from 18.6 to 343.8 μg/L with a mean of (135.97 ± 85.07µg/L). Public health, technological and economic importance of Betalactam antibiotic residues in milk were discussed.