الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 77 |  |  |
| | | from | 77 | | |
Abstract
PDA is a common problem in neonates. It has a very high incidence especially in infants weighting 1000 gram or less reaching in some studies up to 60%. Its lines of management vary considerably between different NICUs from prophylactic closure, presymtomatic treatment, symptomatic treatment, individualized management and even surgical ligation. In our study, we wanted to clarify the current situation in our NICU and the role of echocardiography in the management of this disease.
Aim of the work:
The aim of the work is to assess the short term outcome of PDA in neonates admitted to the Neonatal intensive care unit at El Shatby hospital.
Subject and methods:
In our study, we screened 410 neonates admitted to NICU at EL Shatby hospital. Two hundred fifty were preterm and 160 were term. Sixty cases were proved by echocardiography to have PDA at day 4 –day. Forty seven cases were preterm and 13 were term neonates. These cases were examined by echocardiography to demonstrate its heamodynamic significance. They were also followed to demonstrate the closure rates, success rates of different treatments and the final outcome of these cases including mortality and major morbidities.
Results:
In our study the incidence of PDA was 18.8% in the preterm and 8.1% in the term. The incidence in preterm neonates 32 weeks gestational age or less was 29.1% and in neonates weighting 1000 gram or less was 36.6%. It was also noted that the lower the gestational age and birth weight the higher the incidence of PDA. Females were more common to have PDA in the term. Unlikely, the incidence of heart failure in term neonates having PDA was 15.4%.
On following these cases, the closure rate at ten days was 62.2% in the preterm in comparison to 61.5% in the term but at 28 days the closure rate was 94.4% in the preterm in comparison to 66.7% in the term. Ten cases were chosen not to receive medical treatment and their closure rate was 70% and no case developed heart failure. It was also noticed that the closure rate is higher in cases received ibuprofen (72%) in comparison to paracetamo (60%) at the age of 10 days.