الفهرس 
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Abstract
Post stroke depression
Post-stroke depression (PSD) is one of the common emotional disorders afflicting stroke survivors. Previous studies have reported prevalence rates that have ranged from 18% to 61%, depending upon patient selection and criteria used.(123, 124)
The detection of post stroke depression is not always consistent and Diagnosis of PSD is challenging; therefore, it often remains unrecognized and/or undertreated.(191)
The objective of the study was:
To estimate the prevalence rate of post stroke depression among patients with ischemic cerebrovascular stroke admitted to El-Hadara university hospital and to study correlation between post stroke depression, clinical severity and lesion localization.
Descriptive cross sectional approach was selected for conducting this study on 200 patients with ischemic cerebrovascular stroke admitted at El Hadara university hospital
All studied sample will be subjected to the following tools and techniques:
1) A pre-designed structured interview questionnaire will be used to collect the following data
a. Socio-demographic data as age, sex, residence, educational level.
b. Medical and psychiatric history.
c. Family history of psychiatric illness.
2) Full neurological evaluations.
3) Neurological deficit is quantified according to national institute of health (NIH) stroke scale.
4) CT brain for lesion localization or MRI when indicated.
5) Semi structured interview using Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM IV TR) criteria for diagnosis of major depressive disorder (MDD).
6) Hamilton Depression Rating–17 item version (HDRS-17) to assess severity of depression.
The Following Results were obtained:
1) Seventy eight patients (39%) were complaining of depression (post stroke depression) according to (DSM IV TR) criteria of major depression disorder. The Hamilton Depression Rating scale score of the studied cases ranged between 2 and 18 with a mean of 7.33 ± 4.46.Forty six patients (23%) had mild depression while thirty two patients (16%) had moderate depression.
2) Correlation between demographic data and presence of depression post stroke showed:
a) A Significant statistical correlation between female gender and occurrence of post stroke depression.
b) A significant statistical correlation between living in rural areas and occurrence of post stroke depression.
c) There was no statistical significant correlation between age of the patients and occurrence of post stroke depression.
d) There was no statistical significant correlation between the occupational history and occurrence of post stroke depression.
e) There was no statistical significant correlation between the marital status of the patient and occurrence of post stroke depression.
3) Correlation between presence of risk factors of stroke and occurrence of post stroke depression showed:
No statistical significant difference between occurrence of post stroke depression and presence of DM, hypertension, cardiac disorders, dyslipidemia or smoking as a risk factor of ischemic stroke.
4) Correlation between the onset of the ischemic stroke and the occurrence of post stroke depression showed :
Frequency of occurrence of depression was higher in early stroke durations than in late durations with a statistical significant difference.
5) Correlation between the radiological findings and the occurrence of post stroke depression showed :
a) A significant statistical correlation between depression post stroke and sizable infarctions.
b) A significant statistical correlation between depression post stroke and infarctions that were subcortical or both cortical and subcortical, while cortical infarctions had insignificant statistical correlation with depression post stroke.
c) Infarctions that affected the frontal lobe or the basal ganglia had significant statistical correlation with post stroke depression while these affecting temproparietal lobes, occipital lobes, white matter or posterior fossa had no significant correlations.
d) There was no statistical significant correlation between laterality of infarctions (either right sided, left sided or bilateral infarctions) and occurrence of post stroke depression.
eA significant statistical correlation between presences of edema around the infarct area and occurrence of post stroke depression.
f) A significant statistical correlation between presences of hemorrhagic transformations and occurrence of post stroke depression.
6) Correlation between the severity of post stroke depression by Hamilton score and severity of stroke by NIH stroke scale showed that :
There was positive correlation between the severity of Hamilton depression rating scale and the severity of the ischemic stroke using NIH stroke scale as the severity of depression increased in patients with marked clinical disability.