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Abstract Prediction of ovarian response is vital for the counseling and management of infertile couples in clinical practice. The prediction criteria used by clinicians usually include many characteristics, such as the outcome of previous IVF cycles, the woman’s advanced age, the presence of short menstrual cycles and previous ovarian surgery. Markers of ovarian reserve are regularly used to predict poor ovarian response and a suboptimal response to gonadotrophin stimulation is suspected in the presence of high levels of FSH and/or estradiol, or more recently on the basis of a low AFC or reduced levels of AMH. AMH substantially inhibits the initiation of primordial follicle growth and contributes to normal folliculogenesis by enhancing the role of FSH in cyclic recruitment of follicles. Clinically, AMH can serve as a reliable ovarian reserve marker independent of gonadotropins levels. |