الفهرس 
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Abstract
The study included 40 preterm infants with clinically suspected sepsis who were randomly assigned to one of two equal groups, 20 septic preterm infants received SMOFlipid 20% (group I) and 20 preterm infants received Intralipid 20%. As regards the cytokines studied; IL-6 and TNF-α, we found that both serum level of IL-6 and TNF-α decreased significantly on 7th day post-randomization in each of the SMOFlipid and Intralipid groups with no significant differences of their delta changes when we compared both groups. Moreover, the serum level of TNF-α was significantly higher in SMOFlipid group compared to Intralipid group both at the start of randomization and after 7 days of PN administration. This was not attributable to the increased incidence of LOS among septic infants included in the SMOFlipid group as its level showed no a statistically significant difference between EOS and LOS septic preterm infants included in our study. As regards the secondary outcomes studied, we did not find any significant difference between both SMOFlipid and Intralipid groups included in our study and either the need for inotropes, duration of mechanical ventilation, duration of antibiotic treatment, duration of hospitalization nor mortality rate. However, on 1st day of randomization, TNF-α level showed significant positive correlation to mortality rate while it had no significant positive or negative correlation to duration of mechanical ventilation, duration of antibiotics nor duration of hospital stay in both SMOFlipid and Intralipid groups, while serum IL-6 had no significant positive or negative correlation to any of the secondary clinical outcomes studied in both SMOFlipid and Intralipid groups.