الفهرس 
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Abstract
Phytochemical study of the crude (70% EtOH) extract of Brahea armata S.Watson afforded the isolation and identification of 14 compounds of diverse chemical classes; stigmasterol (1), β-sitosterol (2), 3′,4′,7-trihydroxyisoflavone-4′-methylether-7-O-2E-butenoyl-β-D-glucopyranoside (3), 6,7-dihydroxy-3-(4-hydroxybenzyl) coumarin (4), scortechinone V (5), scortechinone B (6), tricin (7), tricin-7-O-rutinoside (8), quercetin-3-glucoside (9), kaempferol-3-glucoside (10), isorhamnetin-3-glucoside (11), apigenin-6-C-arabinoside-8-C-glucoside (isoschaftoside) (12), veralkamine-O,O- diAc (13) and baikeidine (14). Some of these secondary metabolites were characterized by using spectroscopic data; 1D (1H and 13C), 2D (HSQC and HMBC) NMR as well as MS analyses and the other structures of minor constituents were confirmed by HRESI-MS analysis. The crude extract showed significant hepatoprotective ability against paracetamol–induced toxicity at dose of 125 mg/kg body weight. Also, it has a marked antioxidant activity (123.6%) at concentration 50 µg/ml by using DPPH free radical assay. In addition, this crude extract was of a weak cytotoxicity activity against HepG2 cell lines at different concentration (10-80 µg/ml) and it has a significant antimicrobial activity against the tested micro-organisms with a powerful antifungal activity against Aspergillus niger.
Keywords: Brahea armata; Secondary metabolites; Hepatoprotective; Antioxidant; Cytotoxicity; Antimicrobial activity.