الفهرس 
Chronic kidney disease
Hematologic Consequences of chronic Renal FailureOnly 14 pages are availabe for public view
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Abstract
Chronic renal failure (CRF) is used to describe a patient who
has residual renal function of less than 30%, defined as progressive
and irreversible deterioration in renal function; a situation in which
recovery of renal function is not likely.
The sex hormones are susceptible to significant
pathophysiological alterations in chronic renal failure, which may
lead to delayed or arrested pubertal maturation.
The objective of this study is to evaluate the Testosterone
hormone level in male children and adolescents and Estradiol
hormone in female children and adolescents with chronic renal
failure on hemodialysis therapy.
The study was conducted in the Department of Nephrology,
Pediatric hospital, Tanta University and included twenty children and
adolescents (10 males and 10 females), their age ranged from 10-18
years with proven ESRD (End Stage Renal Disease) of at least one
year duration on regular hemodialysis therapy.
The study included also twenty age and sex matched healthy
individuals as a control group.
The patients were subjected to history taking, clinical
examination including pubertal assessment by Tanner’s classification
of puberty and laboratory investigations including kidney function
tests, complete blood count, serum albumin and electrolytes.
Hormonal assay was measured in both patients and control
group including Testosterone in males and Estradiol in females.