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العنوان
The Role of Serum Interleukin-6 and Interleukin-8 in
the Early Diagnosis of Infection in Neutropenic
Children with Hematological Malignancies \
المؤلف
Wali,Iman Ezzat.
هيئة الاعداد
باحث / ايمان عزت والى
مشرف / سمية عبد اللطيف عيسى
مشرف / حميدة عبد الحميد جوهر
مشرف / علاء محمد على
تاريخ النشر
2003.
عدد الصفحات
230P.;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب
تاريخ الإجازة
1/1/2003
مكان الإجازة
جامعة القاهرة - كلية الطب - ) ميكروبيولوجى
الفهرس
Only 14 pages are availabe for public view

from 230

from 230

Abstract

ln the prt:!sent tudy infection was searched for among febril
neutropenic children having hematological malignancies, and the result were correlated with the
serum interleukin-6 (IL-6) and interleukin-8 (IL 8); as possible early diagnostic markers
of severe life threatenin infections. Positive microbiological find ings were detected in 20 out
the 30 patients (66.66%); 6 patients (30%) had bacteria l infections, on (5%) had fungal
infection, and nine (45%) had viral infections. Eight o of the 9 viruses were detected in oral
swabs, while 1 was detected by ce culture of PBLs. Mixed microbiologic find ings were found in 4
out the 20 patients; 1 patient had a mixed bacteri l infection, another patien had both a
bacterict1 infect ion an<l a virus detected by ceii cu1ture of PBL and each of 2 of the patients
had a virus detected orally and another i cell culture of PBLs. However, serum IL-6 and IL-8
failed to show significant correlation with any of the detected infections.