الفهرس 
Anemia in critically ill patientsOnly 14 pages are availabe for public view
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Abstract
Background:Anemia of critical illness is a deficiency of blood oxygen carrying capacity that is clinically characterized by diminished tissue oxygenation and complicated by end-organ dysfunction.The etiology may be categorized into blood loss and reduced red blood cells production,Trauma,surgery,hemorrhagic complications,and lab.draws compound the effects of functional iron deficiency and blunted erythropoietic response.Allogeneic RBCs transfusion is currently one of the principal interventions for acute treatment of anemia of critical illness.The severity of anemia and subsequent blood transfusion associated with substantially higher risks of morbidity and mortality.Recombinant human erythropoietin (rHuEPO) is widely used to promote RBCs production and reduce blood transfusion in the icu.
Objectives: to discuss hematological derangements in critically ill patients.
Methodology: the study conducted in critically ill patient.
Conclusion:Anemia of chronic disease,or anemia of chronic inflammation,is a form of anemiaseen in chronic infection,chronic immune activation,and malignancy.These conditions all produce massive elevation of Interleukin-6,which stimulates hepcidin production and release from the liver,which in turn reduces the iron carrier protein ferroportin so that access of iron to the circulation is reduced.hepcidin is the central actor in producing anemia of chronic inflammation,Thrombocytopenia often occurs as a result of a separate disorder,such as leukemia or an immune system problem, or as a medication side effect.Coagulation abnormalities are commonly found in critically ill patients such as thrombocytopenia, prolonged global coagulation times, reduced levels of coagulation inhibitors, or high levels of fibrin split products.