الفهرس 
Human Chorionic GonadotropinOnly 14 pages are availabe for public view
 |  | from | 126 |  |  |
| | | from | 126 | | |
Abstract
Background: Implantation is a complex initial step in the establishment of a successful pregnancy. Although embryo quality is an important determinant of implantation, temporally coordinated differentiation of endometrial cells to attain uterine receptivity and a synchronized dialog between maternal and embryonic tissues are crucial. Aim: The aim of the present study is to investigate the value of intrauterine injection of hCG at day of ovum pick-up in patients undergoing intracytoplasmic sperm injection in an attempt to improve implantation and pregnancy rates on patients with recurrent implantation failure. Patients and Methods: The recent study was designed as a prospective case-control, randomized, single blinded study, from February 2015 to January 2016, conducted at ART unit of Ain Shams University, maternity hospital. One hundred participants were assigned into the study, who were prepared to undergo an ICSI trial after a failed previous cycle or more. Patients were divided in to two groups: group (1): The study group; included 50 patients who were injected by 500 IU of hCG intrauterine at the day of ovum pick-up. group (2): The control group; included 50 patients, age matched, who went through the study without intrauterine injection. Results: The current study revealed that: Conclusion: it was found that this approach significantly improved pregnancy and implantation rates, with even improvement of the endometrial thickness at the day of embryo transfer; however miscarriage rates were non-significant between both groups.