الفهرس 
Surgical Anatomy and Histology of Pancreaticoduodenal TriangleOnly 14 pages are availabe for public view
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Abstract
Background: A gastrinoma is a gastrin-secreting tumor.More than 80% of gastrinomas arise from a triangle defined as the union of the cystic and common bile duct superiorly, the neck and body of the pancreas medially, and the second and third portions of the duodenum inferiorly. Rarely, primary tumors as well occur in a variety of ectopic sites, including the body of the stomach, jejunum, peripancreatic lymph nodes, omentum, splenic hilum, liver, gallbladder, ovary, and the common bile duct. Over 50% of gastrinomas are malignant and can metastasize to regional lymph nodes and the liver.
Aim of the Work: The aim of the work is to evaluate the recent modalities in diagnosis and management of gastrinoma in pancreaticoduodenal triangle and how to avoid missing cases of gastrinoma.
Methodology: The management of gastrinoma has developed due to advances in medical therapies, diagnostic and imaging investigations and improvements in surgical technique. Gastrin has been identified as the humoral agent responsible for Zollinger-Ellison syndrome.
Conclusion: Zollinger-Ellison syndrome is characterized by severe peptic ulceratons, hypersecretion of gastric acid, and non-beta islet cell tumors of the pancreas. Further studies with longer follow-up are necessary to conclusively describe the natural history of this condition, identify factors predictive of recurrence and survival, and make categorical recommendations regarding treatment and to avoid missing cases of gastrinoma.