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Abstract Introduction of acute kidney injury was mentioned. Types of AKI in liver cirrhosis was listed. Urinary NGAL and its measurement importance was discussed. Concerning diagnostic performance of uNGAL in differentiating the different types of AKI, uNGAL has good diagnostic performance in the differentiation, uNGAL levels were significantly different in each category of AKI: highest in iAKI, intermediate in HRS and low in prerenal disease. Furthermore, uNGAL levels in patients with prenrenal azotemia were similar to those with normal kidney function. Urinary NGAL has not only potentiality to detect AKI but also has the ability to differentiate cause of AKI as shown in the current study that revealed uNGAL > 30 ng/mg, 15-39 ng/mg, 39-143 ng/mg and >143 ng/mg had the highest characteristics as a diagnostic marker for detecting AKI, diagnosis of prerenal group, HRS and ATN patients respectively. |