الفهرس 
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Abstract
Helicobacter pylori (HP) is associated with over 90% duodenal ulcer, 80% gastric ulcer, mucosa-associated lymphoid tissue lymphoma and gastric adenocarcinoma So its eradication success could cure this diseases and prevent its complications. This study was performed to compare the efficacy of different regimens of triple therapy for treatment of gastric and duodenal ulcer due to HP. This study was carried out on 100 HP positive patients with gastric and duodenal ulcer were enrolled into six groups as follow: group (A) included 18 patients and received omeprazole 20 mg,tinidazole 500 mg and clarithromycin 250 mg twice daily for 7 days (O20T500C250-7d/n=18). group (B) included 18 patients and received the same regimen used in group A for 14 days (O20T500C250- 14d/n=18). group (C) included 15 patients and received omeprazole 20 mg,tinidazole 500 mg and doxcycline 50 mg twice daily for 7 days (O20T500D50 – 7d/n=15). group (D) included 15 patients and received the same regimen used in group C for 14 days (O20T500D50 – 14d/n=15). group (E) included 17 patients and received esomeprazole 20 mg,amoxycillin 1gm and clarithromycin 500 mg twice daily for 7 days (E20A1gmC500-7d/n=17). group (F) included 15 patients and received the same regimen used in group E for 14 days (E20A1gmC500– 14d/n=17). HP eradication was confirmed by histopathological examination and biopsy urease test (CLO test) at least 8 weeks after cessation of therapy. Results: HP eradication rates were as follow group (A) 66.66%, group (B)72.2%, group (C) 53.3%, group (D) 60%, group (E) 88.23% and Group(F)100%. Conclusion: (E20A1gmC500 -14d) is the highest active regimen for the eradication of helicobacter pylori.
Keywords: Helicobacter pylori, Gastric ulcer, Duodenal ulcer, Triple therapy.