الفهرس 
Unexplained InfertilityOnly 14 pages are availabe for public view
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Abstract
Introduction: Unexplained infertility (UI) is a term used to describe infertile couples in whom standard investigations, including semen analysis, tests of ovulation and tubal patency, have failed to detect any gross abnormality.
Aim of the Work: To compare the effect of endometrial scratching/non scratching on the results of IUI in cases with unexplained infertility regarding to both chemical and clinical pregnancy.
Patients and methods: Randomized controlled trial (RCT) involving patients undergoing IUI treatment. Patients found eligible for the study were offered to undergo day 7 endometrial injury of the same IUI cycle. The study was carried out in clinical IVF & ART unit at faculty of medicine Ain Shams University Hospital. During the preselection phase inclusion and exclusion criteria were applied on 88 patients.
Results : The results of this study showed that the pregnancy rates in case group (18.2%) were higher than the pregnancy rates in control group (13.6%) but the difference was not significant.
Conclusion: The result of this study revealed that local mechanical injury to the endometrium by modified cook catheter in the same cycle of IUI might enhance uterine receptivity and improves the chemical and clinical pregnancy rate in women with unexplained infertility but with no significant value. This procedure is safe, easy and without any complications.
Recommendations: Further work will explore the mechanism of increased receptivity to implantation of the injured endometrium. This will involve molecular studies to identify the action of proteins or other factors that are released when the endometrium was injure.