الفهرس 
Metabolic SyndromeOnly 14 pages are availabe for public view
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Abstract
Background: Reports in previous literature have referred to the close association between aging, metabolic syndrome and increased cardiovascular risk with 3-4 fold increased risk of myocardial infarction.
Aims: The present study was designed to investigate the potential of a low intensity swim –exercise program of 4-week duration to protect the heart against ischemic reperfusion injury in aged female rats with metabolic syndrome.
Methodology: The present study was performed on 90 Wistar female rats, initially weighing 260-310 grams (age of rats was between 15 -19 months). Rats were purchased from Abo-Rawash (Giza. Cairo) and were housed in the Physiology Department Animal House, Faculty of Medicine, Ain Shams University under standard conditions of boarding at room temperature 22±1 ° C.
Results: Throughout the 12 week- study period, the percent of deaths was 42% in the control rat group (C), 61% in the metabolic syndrome - sedentary rat group (MS) and 28.5% in the metabolic syndrome-swim exercised (ME) rat group due to drowning. The final number (n) of rats in the three studied rat groups was C (n=17), MS (n=15), ME (n=15). On the start of the study, control (C) and metabolic syndrome rat groups (M) showed insignificant differences in their body weight, body mass index, waist circumference and arterial blood pressure values.
Conclusion: Early life style intervention of metabolic syndrome by low intensity exercise program can promptly improve the cardiovascular high risk components of the metabolic syndrome which could improve the outcome of a subsequent incident of cardiac ischemic reperfusion injury.