الفهرس 
Symptoms of COPDOnly 14 pages are availabe for public view
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Abstract
Aim of the Work: Measuring 8 isoprostane in exhaled breath condensate (EBC) of COPD patients as a biomarker of oxidative stress.
Patients and Methods: This study was conducted at Ain Shams University Hospitals and included patients with chronic obstructive pulmonary disease diagnosed according to the criteria of the Global Initiative for chronic Obstructive Lung Disease. The cases were divided into two groups, group A (included 80 cases having COPD), group B (control group) included 16 healthy persons. All the patients were subjected to arterial blood gas analysis, spirometric lung functions, Spirometry was done at the same hour of measurement of the exhaled breath condensate 8_isoprostane using exhaled breath condensate apparatus was assessed.
Results: spirometry showed worsening of lung functions in COPD cases which increased with the severity of the disease.
8-isoprostane increased in very severe COPD cases and correlated significantly to the severity of the disease.
Conclusion: Measurement Of 8-Isoprostane In Exhaled Brreath Condensate is a promising non invasive biomarker in COPD patients.
KEYWORDS: Exhaled breath condensate; 8_isoprostane; COPD;