الفهرس 
EPIDEMIOLOGY AND SURGICAL ANATOMY OF THE LIVEROnly 14 pages are availabe for public view
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Abstract
Colorectal cancer is the third most commonly diagnosed cancer with approximately half of the patients developing liver metastases during the course of their disease. Preoperative evaluation requires a complete medical evaluation to determine the patient’s suitability for surgery as well as detailed anatomic imaging to determine the location of the liver tumors and to exclude extra hepatic metastases. Radiological evaluation is needed not only to identify extrahepatic disease but also to assess the adequacy of liver parenchyma after surgery. In addition to the patient evaluation, liver function tests are evaluated to assess the synthetic function of the liver; combined with radiological findings, these tests can aid in the decision-making process. Modern multimodal therapies have improved the overall survival. Liver resection remains the most important modality in the treatment of colorectal liver metastases. The evolution of the criteria for resectability has resulted in more patients being offered a hepatectomy. This is further augmented with the utilization of adjuncts to liver resection, including portal vein embolization and local ablative techniques. Two-stage hepatectomy is also being used to increase resectability. Overall survival is improved by the deployment of new chemotherapeutic agents and the use of combination chemotherapy. Neoadjuvant chemotherapy is a promising development in the treatment of colorectal liver metastases. Patients with colorectal liver metastases can achieve long-term survival. A multidisciplinary approach is essential in the management of these patients.