الفهرس 
Induction of Abortion
Teratogenicity of the drugOnly 14 pages are availabe for public view
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Abstract
Objective: To compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of pregnancy in second trimester abortion.
Study design: two-arm placebo controlled trial.
Patients: Patients fulfilling inclusion criteria will be divided into two groups each one will be 200 patients(more than sample size number) to avoid the DROP ín the size of the study¶
group (A):
200 patients will receive misoprostol without letrozol¶
group (B):
200 patients will receive misoprostol without placebo¶
Main outcome(s):letrozole role in induction of abortion.
Result(s): Only the need for oxytocin for augmentation of abortion was found to be a significant fact; between two groups
Conclusion: The conclusion of our study is there was a significant difference between letrozole group and placebo group in the need for oxytocin, completed medical abortion and surgical evacuation.
Key words: EVA: Electric vacuum aspiration; MVA :Manual vacuum aspiration; OHSS :Ovarian hyperstimulation syndrome; PR :Progest-erone receptor; RR: Relative risk; NNT: Number needed to treat