الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 91 |  |  |
| | | from | 91 | | |
Abstract
Rheumatoid arthritis is the most common form of inflammatory arthritis that was first distinguished in the mid-nineteenth century.
Antimalarials are one of the most commonly used non biologic Disease-modifying antirheumatic drugs (DMARDs). Although they are considered from the safest antirheumatic drugs, yet their known toxic retinal effect had been the reason of worry of physicians and ophthalmologists and efforts for its screening and preclinical detection were done meticulously.
In the review of literature, the most commonly used from antimalarials are Chloroquine and Hydroxychloroquine. It’s proved that they have many ocular side effects as CQ retinopathy being the most serious because it’s irreversible; made most of recent studies focusing on early monitoring of chloroquine retinopathy to detect it when it’s still reversible.
This compartive study aimed to detect the possibility of using SD-OCT as screening tool of patients taking chloroquine for treatment of rheumatoid arthritis. We selected the patients from Menofiya university hospital, Rheumatology clinic. The patients underwent full ophthalmological examination, and SD-OCT scanning.
There is retinal thinning in the form of Foveal , parafoveal and perifoveal regions occurred in rheumatoid patients treated with chloroquine compared to the control group.
The conclusion of the study states that SD-OCT is an effective tool for screening of preclinical chloroquine retinopathy.