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Abstract Title: Spectroscopic characterization and biological activities of some transition metal complexes . The thesis comprises of five chapters: Chapter 1 includes the introduction and a literature survey on quinoline azodye ligands, their metal complexes, electrical properties, optical properties and potentiometric studies. Chapter 2 concerned with the experimental work. The following ligands (HL n ) were prepared: HL HL HL HL HL 1 2 3 4 5 : 5-(2-(4-methoxyphenyl)diazenyl)quinolin-8-ol. : 5-(2-(4-methylphenyl)diazenyl)quinolin-8-ol. : 5-(2-phenyldiazenyl)quinolin-8-ol. : 5-(2-(4-chlorophenyl)diazenyl)quinolin-8-ol. : 5-(2-(4-nitrophenyl)diazenyl)quinolin-8-ol. Ru(III) complexes were prepared from the reaction of the ligands (HL and HL [Ru(L n 5 ) with [RuCl )(AsPh 3 ) 2 (Cl) 2 3 (AsPh ].xH 2 O. 3 ) 2 CH 3 OH]. The formed complexes are trans- The synthesized ligands and their Ru(III) complexes were investigated by elemental analysis (C, H and N), molar conductivity measurements, magnetic measurements, spectral studies (IR, electronic, mass, studies (TGA), X-ray, ac conductivities and optical properties. 1 H and 13 1 , HL C NMR), thermal 3 Chapter 3, Chapter4 and Chapter 5 include Results and Discussion Chapter 3 includes the preparation and characterization of quinoline azodye ligands (HL [Ru(L n )(AsPh n 3 ) and their Ru(III) complexes of the type trans- ) 2 (Cl) 2 ].xH 2 O by elemental analysis, IR and UV-Vis. spectra as well as Magnetic susceptibility, electrical conductivity, X-ray and thermal measurements. The molar conductance measurements proved that all the complexes are non-electrolyte. IR spectra show that the ligands (HL monobasic bidentate ligand by coordinating via the nitrogen atom of the azomethine group (C=N) and oxygen atom of the phenolic OH group with the displacement of the hydrogen atom from the later group, thereby forming a five-membered chelating ring and concomitant formation of an intramolecular hydrogen bond. The calf thymus DNA binding activity of the ligands (HL HL 3 and HL 5 ) and their Ru(III) complexes (1-3) were studied by absorption spectra. The antibacterial activities of the investigated compounds were tested against two local Gram positive bacterial species (Bacillus cereus and Staphylococcus aureus) and two local Gram negative bacterial species (Escherichia coli and Klebsiella pneumoniae) on nutrient agar medium. Also, the antifungal activities were tested against four local fungal species (Aspergillus niger, Alternaria alternata, Penicillium italicum and Fusarium oxysporium) on DOX agar medium. The mechanism and the catalytic oxidation of cyclohexanol by trans[Ru(L n )(AsPh 3 ) 2 (Cl) 2 ].xH 2 n ) act as a O with periodic as co-oxidant were described. The molecular and electronic structures of the 1 , investigated compounds (HL n ) were also studied using quantum chemical calculations. The optimized bond lengths, bond angles and calculated the quantum chemical parameters for the ligands (HL n ) were investigated. Chapter 4 included the proton-ligand dissociation constant of the ligands (HL n ) and their metal-ligand stability constants with (Mn(II), Co(II), Ni(II) and Cu(II) have been determined potentiometrically. The potentiometric studies were carried out in 1M (KCl) and 50% (v/v) DMF-water mixture. The effect of temperature was studied at (298, 308 and 318 K) and the corresponding thermodynamic parameters (G, H and S) were derived and discussed. The stability constants of the formed complexes increases in the order Mn(II), Co(II), Ni(II) and Cu(II). The dissociation process is non- spontaneous, endothermic and entropically unfavorable. The formation of the metal complexes has been found to be spontaneous, endothermic and entropically favorable. Chapter 5 describes the ac conductivity (σ ligands (HL n ) in the frequency range 10 2 ac –10 ) and dielectrical properties of the 5 Hz and temperature range 293– 509 K. The temperature and frequency dependence of the real and the imaginary dielectrical constants are studied. The values of the thermal activation energies of electrical conductivity (E 1 and E 2 ) for derivatives under investigation were calculated and found to be in the range of 0.03-0.26 and 0.2-1.31 eV, respectively, depending on the substituent and frequency. The conductivities are found to be dependent on the structure of the compounds. The conduction mechanism was investigated for all the derivatives under investigation. The ligands (HL 1 , HL 2 and HL to be controlled by correlated barrier hopping model and the ligands (HL HL 5 ) be controlled by small polaron tunneling mechanism. The values of maximum barrier height (W m ) were calculated. The optical absorption properties of the ligands thin films were investigated. The absorption coefficient (α) spectra reveals two absorption peaks which are assigned as π-π * and n-π * transitions. The optical energy gap (E investigated near the absorption edge and found to be in the range of 1.34- 2.26 and 1.47-1.69 eV for direct and indirect optical transitions, respectively. 4 ) were found g 3 and ) was |