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Abstract The spine is a common site for bone metastasis for a number of cancers.Spinal metastases can lead to a considerable number of complicationswhich result in significant morbidity, reduction in quality of life and survival. In this retrospective study, the files of 350 patients with spinal bone metastases presented to Alexandria Clinical Oncology and Nuclear Medicine Department (ACOD), Alexandria Main University Hospital during the period from January 2003 to December 2012 were reviewed to identify the clinic-pathological data, risk factors, prognosis including local control and overall survivalwith assessment of treatment results, toxicity and complications. The files in this retrospective study were reviewed and data were collected including the following: demographic data,medical history, histopathological data, clinical data, treatment modalities and treatment outcomes. In this study, we found that these patients constituted 1.41% of the total patients suffered from malignant tumors and presented to ACOD during the same period.The age of all patients included in the study ranged from 40 to 70 years.Female patients presented with higher percentage (60.9%) than male patients (39.1%) with male to female ratio 1: 1.55. In the current study, performance status according to ECOG score; (35.1%) had score 1, 22.9%had score 2, 16.3% had score 3 and 1.7% had score 4 while data on score were unknown in 24% of patients. In this study, the origin of the tumor in the majority of cases was breast cancer (31.1%), followedby prostate cancer in17.7% and Multiple Myeloma(M.M.) in 17.1%. |