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العنوان
Association of Pro 12 Ala Polymorphism in PPAR-g Gene with Sepsis Disease Severity and Outcome in Egyptian Neonates /
المؤلف
Mohamed,Shimaa Rafat
هيئة الاعداد
باحث / شيماء رأفت محمد
مشرف / رباح محمد شوقي
مشرف / طارق مصطفي كمال
تاريخ النشر
2016
عدد الصفحات
183.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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from 183

Abstract

So there was a strong statistical significant difference between patients with neonatal sepsis and the normal control group as regards prevalence of PPAR-g gene polymorphism in occurrence of neonatal sepsis and its severity. The percentage of C allele among patients group was 28.33% nearly equally distributed between homo- and heterozygosity while the G alleles among patients group was detected in 71.66% of with more tendency to be in homozygosity (56.66%). On the other hand, the percentage of G allele among control group was 5% and appeared in heterozygosity only, while the percentage of C allele among control group was 95% with more prevalence to be in homozygosity (90%), thus there is statistical significant difference between patients group and the control group which may suggest high risk for occurrence of neonatal sepsis and PPAR-g G allele. There was a significant statistical difference between genotypes in correlation with age but not significant for gender