الفهرس 
Definition and epidemiologyof hypertensionOnly 14 pages are availabe for public view
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Abstract
Introduction: Left ventricular adaptation to hypertension include the development of left ventricular hypertrophy and several geometric alterations. The myocardial performance index (MPI) is a combined index of systolic and diastolic dysfunction and has been shown to correlate significantly with other conventional indices. The MPI has proved to be a reliable method for the evaluation of LV systolic and diastolic performance and prognostic value in many kinds of heart disease. This study examined the association between the MPI and left ventricular geometric patterns among hypertensive Patients.
Methods: We performed echocardiography on 100 hypertensive patients and 20 control subjects. We compared the control subjects with normal geometry (NG) with match age and sex. We grouped the left ventricular hypertrophy into three geometric patterns based on left ventricular mass index and relative wall thickness. The MPI index was obtained from the summation of the isovolumic relaxation time and the isovolumic contraction time, divided by the ejection time, LVH was classified according to its severity and correlated with MPI.
Results: Among the hypertensive subjects, 36 (36%) had concentric hypertrophy, 14(14%) had concentric remodeling, 20 (20%) had eccentric hypertrophy, and 30 (30%) had normal geometry. The MPI was high in all left ventricular patterns with significant higher values among the hypertensive patients with concentric hypertrophy (CH), eccentric hypertrophy (EH) ,concentric remodeling (CR) as compared to hypertensive patients with normal geometry (0.6 ± 0.06, 0.5 ± 0.07, 0.48 ± 0.07 vs. 0.47 ± 0.11, respectively).
Conclusion: Among hypertensive patients, LV systolic and diastolic functions (using the MPI index) were impaired in all subgroups of hypertensive patients according to their left ventricle geometry compared to the control group. This impairment was more advanced in patients with concentric and eccentric hypertrophy.