الفهرس 
Liver transplantationOnly 14 pages are availabe for public view
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Abstract
Living donor liver transplantation (LDLT) is now an accepted treatment modality for end-stage liver disease. It has become an alternative in the era of organ shortage.
But there is an essential risk related to liver resection for healthy donors. Therefore, an explanation of LDLT’s risks must be made to both recipients and donors who decide to receive this treatment option. Preoperative evaluation of potential donors for living-donor liver transplantation (LDLT) enables selecting a suitable donor with optimal graft quality and ensuring donor safety. Thus, preserving the health of the donors and excluding persons from donation if they are not suitable candidates, for either medical or anatomic reasons, should be of utmost priority for the transplant team.
The aim of this study was to identify and analyze the causes of disqualification of Egyptian potential living liver-donors.
The study was conducted on 192 potential donors who were divided into two groups:
Rejected donor group; 126 donor candidates who were excluded due to different causes representing 65.6% of donors.
Successful donor group; 66 donor candidates who already underwent for surgery representing 34.4% of donors.
The study determined the significant differences of different laboratory data between the rejected and the successful donor groups.
A significant statistical differences were found when comparing INR, albumin, creatinine, bilirubin, antithrombin III, alkaline phosphates, factor V leiden mutation, HCV seropositivity, HBcAb positivity, drug abuse, abnormal ALT, portal vein trifurcation and hepatic steatosis between both groups.
A non-significant statistical differences were found when comparing other laboratory data.
The main causes of disqualification were factor V Leiden mutation and viral hepatitis (B & C).