الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 153 |  |  |
| | | from | 153 | | |
Abstract
Jaundice is the commonest clinical diagnosis in neonatal
medicine and is due to elevated unconjugated (indirect) and/or
conjugated (direct) bilirubin levels.
Hyperbilirubinemia is the most common reason for
hospitalization during the first month after birth.
Phototherapy and/or exchange transfusion are the current
modes for treating neonatal hyperbilirubinemia and preventing any
neurological damage.
Eosinophils along with basophils and mast cells, are important
mediators of allergic responses and asthma pathogenesis and are
associated with disease severity.
Recent research has provided that phototherapy associated with
some long-term side effects such as melanocytic nevi and skin
cancer, allergic diseases, asthma, patent ductus rteriosus and retinal
damage.
The aim of this study was to investigate the influence of using
phototherapy in treatment of neonatal jaundice on the serum level of
Eosinophil.
To fulfill this aim, thirty term newborns with neonatal jaundice
were included in this study, having indirect bilirubin levels higher
than 18 mg/dl and thirty healthy newborns were selected as controls.
Blood samples were obtained from hyperbilirubinemic
newborns before and at 72 hours of exposure to phototherapy and
from controls at the examination time.
Our study found that there was increasing in the level of
peripheral eosinophil count after exposure to phototherapy fore 48 to
72hr (P value = 0.073)