الفهرس 
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Abstract
This study was conducted in the department of obstetrics and gynecology at Menoufia University Hospitals. This prospective observational study group comprised 60 women with severe preeclampsia who received intravenous infusion of magnesium sulphate for seizure prophylaxis. Women received 4g and then 1.5g/h. Women had 4-hour and 12-hour levels drawn. Serum Mg levels were considered subtherapeutic at less than 4.9 mg/dL, therapeutic from 4.9 to 8.4 mg/dL, and supratherapeutic at 8.5 mg/dL or more. If the 4-hour value was not therapeutic, the dose was adjusted and a 12-hour level was drawn. Levels at 4 and 12 hours were compared among the women with different BMI classifications and clinical characteristics. The study tried to assess the effect of body mass index on magnesium levels during anticonvulsant prophylactic use of magnesium sulphate in sever preeclampsia.
BMI had highly significant effect on serum Mg level with negative correlation; obese patients were at highly significant risk for having a subtherapeutic serum Mg level when measured at 4hs.
As regard to age, parity, gestational age, maternal and perinatal complication, there was no significant difference in the 3 groups at 4 hours after loading dose of MgSO4 infusion.
65% of normalweight patients had a therapeutic serum Mg level when measured at 4hs. The mean score of deep reflexes were higher before than at 4h of MgSO4 infusion. These differences were high statistically significant with knee reflexes P value<0.001.
There was highly significant difference between deep reflexes in the 3 groups at 4 hours after loading dose of MgSO4 infusion. DTR findings had been shown to be an inexpensive indicator of magnesium levels.