الفهرس | Only 14 pages are availabe for public view |
Abstract Cardiovascular affection in patients with systemic lupus erythematosus may occur in any layer of the heart mostly by autoimmune mechanism and it is one of major causes of morbidities and mortalities among patients with SLE. This retrospective study aimed at detecting the prevalence, onset and presentation of cardiovascular involvement in children and adolescents with systemic lupus erythematosus diagnosed over the period from 2000 to 2014 in Ain Shams University Hospital for children. A retrospective study includes 54 patients with cardiovascular affection of SLE, all patients with SLE underwent revision of hospital records searching for any symptom, sign, Echocardiographic or ECG finding for cardiac affection due to SLE cause and also for age of onset of SLE, sex, duration of SLE, immunological profile, serum lipids. The most common cardiac lesion according to this study was Pericarditis was 50% of cardiac cases, valvular lesion was the second, mitral regurge 25.9%, tricuspid regurge 1.9%, aortic regurge 3.7%, then, pulmonary hypertension 16.7%, left ventricular dilatation 11.1%, right ventricular dilatation 1.9%, left atrial dilatation 7.4%, right atrial dilatation 1.9%, left ventricular hypertrophy 9.3%, myocardial dyskinesia 1.9%, and ejection fraction was less than 40% in 13% of cardiac cases, sinus tachycardia 33.3%, S-T segment elevation 3.7%, prolonged P-R interval 1.9%, bigeminy 1.9%, and premature ventricular contractions (PVCs) 1.9%. |