الفهرس 
HEPTITIS B VIRUSOnly 14 pages are availabe for public view
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Abstract
Background: On a worldwide scale, chronic hepatitis B virus (HBV) infection can lead to advanced liver disease including cirrhosis and hepatocellular carcinoma (HCC). Studies have shown that sustained HBV clearance reduces the risk of disease progression, but it is unclear whether HBV DNA levels in patients with persistent viremia is associated with disease severity. This is an important consideration, because viral load could potentially be used to guide decisions about when to start treatment. Fibro Scan has been considered as a rapid and non-invasive method to assess liver fibrosis in patients with chronic hepatitis B (CHB).
Patients and Methods: A cross sectional study in which 60 patients diagnosed to have chronic HBV. Liver stiffness using FibroScan measured in Kilopascal is used to assess degree if fibrosis divided it into 2 groups. group A with chronic hepatitis B infection with non-advanced fibrosis and group B with chronic hepatitis B infection with advanced fibrosis.
Aim of the Work: Evaluate role of hepatitis B viral load in progression of liver fibrosis measured by liver fibro-scan in patients with chronic HBV infection.
Results: HBV PCR was non-significantly higher among cases with than without cirrhosis and that HBV PCR had no significant diagnostic performance in differentiation between fibrosis stages.
Conclusion: liver stiffness measurements and HBV viral load were not correlated to each other’s, they are both mandatory for assessing degree of liver fibrosis & degree of viraemia.