الفهرس 
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Abstract
Breast cancer is the most common site-specific cancer in women and is the leading cause of death from cancer for women age 40 to 44 years. It accounts for 33% of all female cancers and is responsible for 20% of the cancer-related deaths in women.
Breast MRI has been increasingly used in clinical practice. It has played important roles in breast cancer management, including staging of breast cancer, monitoring of response to neoadjuvant chemotherapy, evaluation of patients with metastatic axillary lymph nodes with unknown primary tumor, screening of breast cancer in women at high risk, and problem solving when findings at mammography and ultrasonography are inconclusive.
Dynamic contrast enhanced (DCE) MR imaging with adequate spatial and temporal resolution, facilitated assessment of both morphologic and enhancement kinetic features, as are described in the Standardized American college of Radiology (ACR) breast imaging reporting and Data system (BI-RADS) MR Imaging Lexicon. New revisions of the MRI lexicon serve to further clarify breast MR imaging reporting, improve lesion diagnosis and management and facilitate patient care.3,4 The goal of the study was to assess the role of Dynamic contrast enhanced magnetic resonance imaging in characterization of breast lesions and to differentiate benign from malignant lesions on the basis of their morphology and signal intensity curve .
Our aim was to study the role of dynamic contrast enhanced MRI in characterization of suspicious breast lesions.
Our study was conducted between January 2014 to January 2016 on 70 patients with suspicious breast or axillary lesions who were referred to the radiology department of Menoufia university hospitals for further assessment by DCE-MRI.
All patients were subjected to full history taking, clinical examination, then, MRI followed by DCE-MRI.
By analysis of DCE-MRI images we found that fourteen cases (20%) of breast carcinoma, out of that five (12.8%) were seen as non-mass enhancing lesion. All mass like lesion were irregular in shape and curve predominantly showing rising and plateau followed be persistent kinetic curve in one case. Forty eight patients (68.6%) showed no enhancement and type 1 curve, and so diagnosed as benign breast lesions. Eight (11.4%) patients showed type 2 plateau curve and so diagnosed as benign, malignant or suspicious according to other MRI criteria.
Calculated sensitivity, specificity and total accuracy of DCE-MRI according to the above specified criteria was 100%, 75% and 89.3% respectively. DCE-MRI had better diagnostic accuracy mainly due to improved specificity and better positive and negative predictive values.