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العنوان
The Role of DW-MRI in Assessment of Treatment Response of Head and Neck Squamous Cell Carcinoma /
المؤلف
Hussein, Mai Alsaeed Mohammed.
هيئة الاعداد
باحث / مي السعيد محمد حسين
مشرف / حسني سيد عبدالغني
مشرف / أماني صابر جرجس
مشرف / منال فايز أبو سمره
الموضوع
Cancer - Tomography. Head and Neck Neoplasms - Diagnosis. Cancer - Diagnosis. Magnetic Resonance Imaging - Methods. Image Interpretation, Computer-Assisted - Methods. Neck - Cancer. Head - Cancer.
تاريخ النشر
2016.
عدد الصفحات
88 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2016
مكان الإجازة
جامعة المنيا - كلية الطب - قسم الآشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Head and neck imaging has been revolutionized during last 20 years. In squamous cell carcinoma (SCC), multislice computed tomography (CT) and new sequences in magnetic resonance (MR) imaging help in tumor staging, which influences patient management and prognosis. New imaging modalities have the ability to differentiate neoplastic from inflammatory lesions., provide essential information about the deep extension of clinically detected masses and delineate additional clinically unsuspected lesions (Agnieszka 2011)
Now, there is growing interest in the application of DWI for the evaluation of the patient with cancer. DWI measurements are quick to perform (typically 1–5 minutes) and do not require the administration of exogenous contrast medium. Thus, these imaging sequences can be appended to existing imaging protocols without a significant increase in the examination time. Furthermore, DWI yields both qualitative and quantitative information that can be helpful for tumor assessment (Yoshikawa et al., 2004)
Our study was carried out between February 2015 and February 2016. It included 30 patients previously diagnosed with squamous cell carcinoma (HNSCC). They were divided into 2 groups:
group (I) Twenty patients were evaluated by DW-MRI imaging within 10 days before treatment, repeated 3 weeks after the start of treatment and a third DW-MRI imaging was performed at the end of treatment (within 6 to 8 weeks).
group (II): Ten patients were coming for post-treatment follow up. DW-MRI was done and compared with their recent post treatment MDCT study and endoscopy .
The aim of our study was to investigate the utility of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) for assessment and early detection of treatment response in head and neck squamous cell carcinomas (HNSCC)
The following data were recorded
• Findings of Conventional head and neck MDCT and MRI examination
• Findings of MR-DWI examination in two groups.