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العنوان
Invasive Fungal Infections after Liver Transplantation/
المؤلف
Arakeeb,Ahmed Hassan .
هيئة الاعداد
باحث / أحمد حسن عراقيب
مشرف / أحمد إبراهيم إبراهيم
مشرف / رامي منير وهبة
مشرف / محمد عثمان طعيمة
تاريخ النشر
2017.
عدد الصفحات
127.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Intensive Care
الفهرس
Only 14 pages are availabe for public view

from 127

from 127

Abstract

Introduction: Liver transplantation is one of the most effective therapeutic op¬tions for patients with certain acute and chronic end-stage liver diseases, Fungal infections in liver transplant recipients have been associated with poor outcome and mortality rates ranging from 65% to 90% for invasive aspergillosis and 30% to 50% for invasive candidiasis.so the clinical diagnosis and treatment of fungal infections after liver transplantation is very important in decreasing mortality in transplant recipients, Prevention and management of Invasive fungal infection in the immunocompromised patient has proven remarkably challenging.
Objectives: This review aims to highlight the different types of invasive fungal infections, risk factors, diagnosis, early detection and antifungal prophy¬laxis and treatment after liver transplantation
Data Sources: Medline databases (PubMed, Medscape, ScienceDirect. EMF-Portal) and all materials available in the Internet till 2017.
Study selection: This search presented 144 articles. The articles studied the role of angiogenesis in dermatological diseases and to purify the most recent studies in this field.
Data Extraction: If the studies did not fulfill the inclusion criteria, they were excluded. Study quality assessment included whether ethical approval was gained, eligibility criteria specified, appropriate controls, and adequate information and defined assessment measures.
Data Synthesis: Comparisons were made by structured review with the results tabulated.
Conclusions: Given the increased risk and poor outcomes in liver transplant recipients who develop fungal infections, early diagnosis and aggressive antifungal prophylaxis should be considered upfront in high-risk patients.The early identification of patients at high risk of developing fungal infections may improve outcomes. Further research is needed to determine the benefits of new molecular and immunological diagnostic assays Concerns about identifying high risk transplant recipients and selecting appropriate antifungal agents are very relevant, and the potential advantages of prophylaxis should be measured against the potential harm.