الفهرس 
Perinatal Development of White MatterOnly 14 pages are availabe for public view
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Abstract
Many preterm and some full tern newborns show different abnormal clinical signs during or soon after birth that may indicate the presence of encephalopathy which could be caused by hypoxic, metabolic or infectious etiologies. Determining the presence of insult, its underlying cause and its extent is very critical as it dramatically affect the management of such neonates.
Magnetic resonance (MR) imaging is the most sensitive technique for assessing the developing brain providing highly detailed images of brain structures without exposing infants to ionizing radiation or health risks; it is increasingly used in clinical practice as the main imaging method for detecting neonatal brain injury.
In neonates and young infants, the standard MRI protocol consist ofT1 and T2-weighted images (WIs) as well as axial diffusion or diffusion tensor images. DWI sequences are very sensitive for detecting acute HIE, whereas gradient (GRE) sequences can detect the smallest amount of hemorrhage