الفهرس 
mecC mediated methicillin-resistant StaphylococciOnly 14 pages are availabe for public view
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Abstract
MRSA is one of the most important pathogens causing a wide range of infections among not only hospitalized patients, but also in the community, with limited choice of antibiotics, making it’s accurate and rapid diagnosis so crucial.
In 2011, a new mecA gene homologue, mecC gene, has emerged. It’s coding for a new Penicillin Binding Protein (PBP2c) which is only 69% identical to PBP2a at the DNA level and 63% on the protein level giving negative results when tested for MRSA using the latex agglutination test or the PCR designed for the detection of mecA gene and also functionally distinct from it making the screening for MRSA using the oxacillin disc by the DD method less reliable. That creates a challenge in the diagnosis of MRSA.
The prevalence of mecC-encoded MRSA vary between different countries with a tendency to increase in some of them and was linked to zoonotic transmition from Livestock.
To the date, studies carried out in Egypt and Africa didn’t detect mecC-positive isolates.
Our current study aimed to phenotypically and genotypically identify mecC-encoded Staphylococci using DD method by both oxacillin and cefoxitin, latex agglutination test, Vitek 2 automated system for both identification and antibiotic susceptibility and PCR using mecC .