الفهرس 
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Abstract
Thalassemia is a hereditary anemia resulting from defects in Hemoglobin production.
Beta-thalassemia, which is caused by a decrease in the production of β-globin chains, affects multiple organs and is associated with considerable morbidity and mortality, accordingly lifelong care is required and financial expenditures for proper treatment are substantial.
chronic liver disease affects a high proportion of patients with beta-thalassemia major; One of the main causes of liver injury in thalassemics are hepatitis C virus (HCV) infection , which is secondary to the regular transfusion regimen.
Our study aimed to study hepatic affection in patients with beta thalassemia in Beni-Suef governorate due to hepatitis C infection including abdominal ultrasonography as a non invasive method for following up the hepatic condition in those patients.
In our study, 15% of patients had positive HCV antibodies detected by ELISA .
Ultrasonographic findings:
-There was a highly significant direct correlation between HCV infection and Ultrasonographic hepatic findings i.e all patients who were found to be HCV positive had hepatomegaly,diffuse texture(denoting fibrosis) and attenuated hepatic
veins(denoting fibrosis). ( p value less than 0.001).
abdominal ultrasonography can be used as a non-invasive method to follow up hepatic condition in Beta thalassemia patients.